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Active ingredient

Pregabalin

Pregabalin is a prescription medicine used to treat neuropathic (nerve) pain, certain types of epilepsy (as an add-on treatment for partial seizures) and generalised anxiety disorder. In many countries it is classified as a controlled drug because of its potential for misuse and dependence. It is available under various brand and generic names and should be used only under medical supervision.

Reviewed by the Kamagra AUS Pharmacy Team on 21 June 2026 · Next review June 2027

Pregabalin medicines we deliver

Browse the full Pregabalin range

6 generic Pregabalin products — same molecule, different brands, formats and pack sizes.

How it works

Pregabalin is structurally related to the neurotransmitter GABA but does not act directly on GABA receptors. It binds to a specific subunit (the alpha-2-delta subunit) of voltage-gated calcium channels in the central nervous system. This binding reduces the release of several excitatory neurotransmitters involved in transmitting pain signals, seizure activity and anxiety, which is thought to underlie its effects across these conditions.

How it is taken

Take pregabalin exactly as prescribed and follow the patient information leaflet. It is taken by mouth and the dose is usually increased gradually at the start of treatment so your body can adjust. It can generally be taken with or without food. Do not change your dose or stop taking it on your own — if you wish to stop, your doctor will normally reduce the dose slowly over at least a week, as stopping abruptly can cause withdrawal symptoms.

Side effects

Common (usually mild and temporary):

  • Drowsiness and sleepiness
  • Dizziness
  • Headache
  • Dry mouth
  • Weight gain or increased appetite
  • Blurred vision

Stop and seek medical help if you experience:

  • Allergic reactions such as swelling of the face, lips or throat, or difficulty breathing
  • Low mood, or new or worsening thoughts of self-harm or suicide
  • Signs of dependence or withdrawal symptoms on stopping
  • Breathing difficulties, especially when combined with opioids or in people with respiratory problems
  • Severe dizziness, fainting or confusion

Safety & who should not take it

  • Do NOT stop pregabalin suddenly — the dose should be reduced gradually under medical guidance to avoid withdrawal symptoms.
  • It commonly causes drowsiness and dizziness — do not drive or operate machinery until you know how it affects you.
  • Pregabalin has a potential for dependence and misuse and is a controlled drug in many countries; take it only as prescribed and never share it.
  • Use caution with alcohol, opioids and other sedating medicines, as the combination can cause dangerous drowsiness and breathing problems.
  • Tell your doctor about all medicines you take and any history of kidney problems, mood disorders, substance misuse or breathing difficulties.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding, as the risks and benefits need careful consideration.
  • Seek urgent medical advice if you experience new or worsening low mood, anxiety or thoughts of self-harm.

Storage

Store in the original packaging at room temperature, away from excess heat and moisture, out of the sight and reach of children. Do not use after the expiry date, and return unused medicine to a pharmacy for safe disposal.

Frequently asked questions

Can I stop taking pregabalin suddenly?+

No. Stopping abruptly can cause withdrawal symptoms such as trouble sleeping, headache, nausea, anxiety and sweating. Your doctor will usually reduce the dose gradually over at least a week.

Is pregabalin a controlled drug?+

In many countries pregabalin is classified as a controlled medicine because of its potential for misuse and dependence. It should be taken only as prescribed and never shared with others.

Can I drink alcohol or take opioids with pregabalin?+

Combining pregabalin with alcohol or opioids can cause excessive drowsiness and serious breathing problems. Discuss any such use with your doctor and follow their advice carefully.

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.