Zopiclone

Zopiclone works on the brain and central nervous system to promote sleep. It enhances the effect of a natural calming chemical called GABA (gamma-aminobutyric acid), which reduces the activity of nerve cells. This produces a sedative effect that can help you fall asleep more quickly, reduce night-time waking and improve overall sleep quality for a short time.

Always take zopiclone exactly as prescribed and as described in the patient information leaflet. It is taken by mouth, usually just before going to bed, and only when you are able to get a full night's sleep.

Common (usually mild and temporary):

• A bitter or metallic taste in the mouth
• Daytime drowsiness, tiredness or feeling 'hungover' the next day
• Dry mouth
• Headache
• Dizziness or light-headedness

• Do not drink alcohol while taking zopiclone; combining the two greatly increases drowsiness and the risk of serious breathing problems.
• Do not drive or operate machinery until you know how zopiclone affects you, as next-day impairment is common; it is an offence to drive while impaired.
• Tell your doctor about all other medicines, especially other sedatives, strong painkillers (opioids), muscle relaxants or medicines for anxiety.
• Use is intended for short-term treatment only; long-term use can lead to tolerance, dependence and difficult withdrawal.
• Tell your doctor before use if you have breathing problems, liver or kidney disease, myasthenia gravis, sleep apnoea, or a history of alcohol or drug misuse or depression.
• Not recommended during pregnancy or breastfeeding, or for children.
• Older adults may be more sensitive and are at greater risk of drowsiness, confusion and falls.

Store in the original packaging below 25°C, away from direct heat, light and moisture, and out of the sight and reach of children. As a controlled medicine, return any unused tablets to a pharmacy for safe disposal.

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