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Erectile dysfunction (ED) is persistent difficulty getting or keeping an erection firm enough for sex, treated here with generic Sildenafil, Tadalafil, Vardenafil and Avanafil tablets and oral jellies.
Generic erectile-dysfunction medicines built on sildenafil, tadalafil, vardenafil and avanafil — the same active ingredients as the well-known branded equivalents, made under Good Manufacturing Practice conditions. The range covers plain tablets, oral jellies, chewables and combination products that pair a PDE5 inhibitor with dapoxetine. All of these are Prescription Only Medicines in Australia: they should only be used on the advice of a registered prescriber who knows your history, and you should read the patient information leaflet supplied with the product before use.

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Reviewed by the Kamagra AUS Pharmacy Team on 5 September 2026 · Next review June 2027
Key facts
Erectile dysfunction (ED) is persistent difficulty getting or keeping an erection firm enough for sex. Occasional difficulty is normal and happens to most men at some point; ED is the pattern that keeps recurring over weeks or months. It becomes more common with age, but it is not an inevitable part of ageing, and it is one of the more treatable men's health problems. Healthdirect Australia publishes plain-English consumer information on it, and it is a sensible first read if the topic is new to you.
The causes divide roughly into physical, psychological and mixed. Physical causes include narrowed or damaged blood vessels, diabetes, high blood pressure, high cholesterol, hormonal changes, nerve injury and the side effects of some other medicines. Psychological causes include stress, low mood, anxiety about performance and relationship strain. Because the erectile tissue depends on small blood vessels, ED can be an early signal of wider cardiovascular disease — which is one reason a proper assessment matters more than simply obtaining tablets. A doctor may want to check blood pressure, blood glucose, cholesterol and sometimes hormone levels.
Everything in this category belongs to a single drug class: phosphodiesterase type 5 inhibitors, usually shortened to PDE5 inhibitors. In simple terms, they block an enzyme that would otherwise break down a signalling molecule involved in relaxing the smooth muscle in blood vessel walls. The practical consequence is that blood flow into the penis is easier to achieve and maintain during sexual arousal. They do not create arousal and they do not work without it — that is a common misunderstanding, and it is the single most useful thing to know about how the class behaves.
Every product listed here is a generic. A generic medicine contains the same active ingredient as an originator brand — sildenafil is the molecule behind Viagra, tadalafil the molecule behind Cialis, vardenafil behind Levitra and avanafil behind Spedra. Generics exist because the originator's patent has expired, which is why they typically cost far less than the branded product. In Australia, the Therapeutic Goods Administration assesses medicines before they can be supplied here, and products it has approved appear on the Australian Register of Therapeutic Goods (ARTG). Many generics sold internationally are made to Good Manufacturing Practice standards for other markets and are not themselves ARTG-registered, so it is worth understanding exactly what you are ordering and discussing it with your prescriber or pharmacist.
Format is the other axis of difference. Standard film-coated tablets are the most common. Oral jellies come in single-serve sachets and are swallowed rather than chewed, which suits people who find tablets difficult. Chewable and effervescent forms exist for the same reason. Some products in the range are combination formulations that add dapoxetine, a short-acting agent used in the management of premature ejaculation, to a PDE5 inhibitor. Combination products are not a default choice — they are only appropriate where a prescriber has decided both components are warranted, and they carry the precautions of both ingredients at once.
One last point on how to use this page. Nothing below tells you what to take, how much, or when — that is not something a retailer can responsibly do, and in Australia it would breach the rules that govern how prescription medicines may be discussed with consumers. What this page can do is explain the differences between the options, set out the safety issues that apply across the whole class, and give you the vocabulary to have a more productive conversation with a doctor or pharmacist.
All four molecules belong to the same class and are used for the same problem; they differ mainly in how long they stay active in the body, the forms they come in, and how they interact with food and other medicines. There is deliberately no dose column here — labelled strength is a matter for your prescriber, not a shopping decision.
| Option | Active ingredient | Formats | Duration profile | Notes |
|---|---|---|---|---|
| Sildenafil | Sildenafil citrate | Tablets, chewables, effervescent tablets, oral jelly sachets | Shorter-acting member of the class | The oldest and most widely studied PDE5 inhibitor, and the one most Australians have heard of. A heavy or fatty meal is described in the approved product information as affecting absorption. Sold here as Kamagra, Fildena, Cenforce and SILDAMAX. |
| Tadalafil | Tadalafil | Tablets, including higher labelled-strength and sublingual lines | Longest-acting member of the class | Stays active in the body considerably longer than the others, which is why it is sometimes described as offering more flexibility. That longer window also means any interaction or side effect lasts longer. Sold here as the Vidalista family. |
| Vardenafil | Vardenafil hydrochloride | Tablets, including combination lines with dapoxetine | Shorter-acting, broadly similar profile to sildenafil | Chemically close to sildenafil and often considered when someone has not tolerated or responded to it. Has particular cautions around medicines that affect heart rhythm. Sold here as Vilitra and Super Vilitra. |
| Avanafil | Avanafil | Tablets | Shorter-acting; the most recently developed of the class | Designed to be more selective for PDE5 than the earlier molecules, which is the stated rationale behind its side-effect profile. Less long-term real-world data exists simply because it is newer. Sold here as the Avana family. |
| Dapoxetine combinations | Dapoxetine, alone or with a PDE5 inhibitor | Tablets (Duratia, and the Super / Extra Super combination lines) | Short-acting; intended for occasional rather than continuous use | Dapoxetine is a short-acting SSRI used in premature ejaculation. Combination products carry the precautions of both ingredients, including SSRI interactions and a caution about fainting. Only appropriate where a prescriber has assessed both problems. |
Swipe the table sideways to see every column.
Duration profiles above are qualitative comparisons drawn from approved product information; they are not a guide to when or how to take anything, and they are not a claim that one option performs better than another. Response varies from person to person. Labelled strength, suitability and any change of medicine are decisions for your prescriber.
1Start with a medical assessment, not a product
ED can be the first visible sign of cardiovascular disease or undiagnosed diabetes. A prescriber will want to know your blood pressure, your other medicines and your cardiac history before any PDE5 inhibitor is considered. Choosing a product before that assessment gets the order backwards.
2Rule out the absolute blockers first
If you take nitrates in any form, or the pulmonary hypertension medicine riociguat, PDE5 inhibitors are not an option at all — this is not a caution to weigh up, it is a hard contraindication. Alpha-blockers and some blood pressure medicines need care rather than exclusion. Bring a full list of what you take, including anything bought over the counter.
3Then think about duration and format
Once a prescriber has confirmed the class is suitable, the practical differences are how long a molecule stays active and what form it comes in. A longer-acting option suits people who dislike planning; a shorter-acting one suits people who prefer a medicine to clear the system quickly. Oral jellies and chewables exist for people who struggle with tablets.
4Review rather than escalate
If a medicine is not working as expected, the answer is a conversation with your prescriber, not a higher labelled strength or a second product. Sometimes the issue is an interaction, sometimes an untreated underlying cause, sometimes a psychological factor that medicine alone will not resolve.
Put briefly: the class is chosen by a prescriber, and the molecule within the class is chosen with them based on your other medicines, your health history and how long you want a medicine to remain active. Formats — tablet, chewable, effervescent, oral jelly — are a matter of practicality. Combination products containing dapoxetine are only relevant if premature ejaculation has also been assessed. Never combine two products from this range, and never use someone else's medicine.
Check the prescription position first
Sildenafil, tadalafil, vardenafil, avanafil and dapoxetine are Schedule 4 Prescription Only Medicines in Australia. Any source that frames itself as a way to skip that step is asking you to take on the risk yourself. Have an assessment with a registered Australian prescriber, and keep the record.
Know what ARTG registration means
The Australian Register of Therapeutic Goods lists the products the TGA has assessed for supply in Australia. Many international generics are made to Good Manufacturing Practice standards for other markets without being ARTG-registered. That is a meaningful difference and you should understand which you are ordering.
Inspect the packaging on arrival
Genuine product arrives in intact manufacturer packaging with a legible batch number and expiry date, an unbroken blister foil, and a patient information leaflet. Spelling errors, smudged printing, missing batch details, loose tablets in a plain bag or a short-dated expiry are all reasons to stop and ask.
Judge the seller, not just the price
A verifiable business address, a working contact route, clear pricing in Australian dollars, a stated dispatch and delivery timeframe, a published returns and complaints process, and a privacy policy that explains what happens to your data. A price far below everything else in the market usually reflects something about the product.
Keep counterfeit risk in mind
ED medicines are among the most counterfeited products in the world precisely because demand is high and people buy them privately. Counterfeits have been found containing the wrong ingredient, the wrong quantity of the right ingredient, or contaminants. This is the practical reason authenticity checks matter more here than in most categories.
Report anything that seems wrong
If a product looks tampered with, or if you have an unexpected reaction, speak to a pharmacist or doctor. Australia has an adverse event reporting system administered by the TGA, and pharmacists can help you use it.
Yes. Sildenafil, tadalafil, vardenafil, avanafil and dapoxetine are Schedule 4 Prescription Only Medicines under Australian scheduling. They should be used on the advice of a registered prescriber who has assessed your cardiovascular health and your other medicines. We do not offer, and cannot offer, a way around that step.
They are the same class working the same way. The main difference is that tadalafil stays active in the body considerably longer, which some people prefer because it removes the need to plan around a narrow window. The trade-off is that any side effect or interaction also persists longer. Which suits you is a discussion for your prescriber, not a ranking.
A generic contains the same active ingredient as the originator brand and, where it has been through a regulatory bioequivalence assessment, is required to deliver that ingredient to the bloodstream comparably. Differences lie in inactive ingredients, tablet appearance, packaging and price. What matters most is where the product came from and whether it was made under proper manufacturing controls.
Australian medicines are classified into schedules that determine how they may be supplied. Schedule 4 means Prescription Only Medicine: a pharmacist may supply it only against a prescription from an authorised practitioner. Schedule 8 is a tighter category for controlled drugs. The TGA and state health departments administer this system.
No. This is an absolute contraindication, not a caution to weigh up. Nitrate medicines for angina and amyl nitrite 'poppers' both act on the same blood-pressure pathway as PDE5 inhibitors, and the combination can cause a sudden, dangerous fall in blood pressure. The same applies to riociguat. If you are ever treated in an emergency, tell the team what you have taken.
An erection that is painful or lasts several hours, sudden loss or reduction of vision, sudden hearing loss or ringing in the ears, and chest pain, severe dizziness or fainting during or after sex all warrant immediate medical attention. In an emergency in Australia, call 000. Do not wait to see whether it settles.
An oral jelly is a different presentation of the same active ingredient in a single-serve sachet. It exists mainly for people who dislike or struggle with swallowing tablets. It is not a stronger or different category of treatment, and it carries exactly the same precautions and contraindications.
By your prescriber, taking into account your health, your kidney and liver function, your other medicines and how you respond. We do not give strength guidance and no online retailer should. If something is not working as you expected, go back to the prescriber rather than changing what you take.
They are different problems. Premature ejaculation is addressed by different agents — dapoxetine is the one that appears in this range, sometimes formulated together with a PDE5 inhibitor in a combination product. Whether a combination is appropriate depends on an assessment of both issues by a prescriber.
No, and it is important to understand that. The ARTG lists what the TGA has assessed for supply in Australia. Generics manufactured for other markets can be made under Good Manufacturing Practice conditions without being ARTG-registered. Ask about the origin of anything you order and discuss it with your pharmacist.
PBS subsidy arrangements are set by the Australian Government and are specific and limited; most people obtain these medicines on a private prescription and pay the full price. Your prescriber or pharmacist can tell you what applies to your circumstances. We are not a PBS supplier.
Orders are dispatched within one business day of payment clearing, and standard delivery runs 2–4 business days Australia-wide. Delivery is free on orders over $150. Everything ships in plain, unbranded outer packaging with nothing on the outside indicating the contents.
For independent, Australian information about the medicines in this range, we point customers to the following bodies. Search for the medicine by name on their sites rather than relying on overseas material.
Important: This is general information, not medical advice, and it is not a recommendation to use any particular medicine. Always read the patient information leaflet and consult a doctor or pharmacist before use.
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